Bendis recently appeared on the Word Balloon podcast. During this podcast they talked about his various projects and he briefly talked about Ultimate Comics Spider-Man. It's around the 1:23:00 mark. He states that issue #22 will be the biggest issue for the series storywise and that it will be Sara Pichelli's last issue before moving over to Guardians of the Galaxy. He continues to say that they will skip forward by a year. He also says that Marquez is taking over art duties full time.