Spidey-Ock is essentially a new character with a new approach to problems and techniques as well as frame of mind. So, does that mean his arch-enemy will change as well? If so, who would be a suitable nemesis for Otto? We do have the likes of Green Goblin and Carnage and stuff who were from Pete's rogues gallery. But who would or could become Otto's arch nemesis from the Spider-Man gallery? What would make the person a nemesis for Spock and be a suitable match for him?