Funniest instances of a small error leading to a huge disaster

[nervmeister]

For example...

What other instances in fiction like this just made you come apart laughing.

[Farealmer]

Baby Guts not being left to die by that band of mercenaries.

[Guy Smiley]

For example...

What other instances in fiction like this just made you come apart laughing.

Reminds me a bit of Monty Python's Salad Days sketch...

[KJ Stewart]

I'm sure Homer Simpson has done something where he moves something tiny that he shouldn't touch, then loads of massive things collapse. But I've been racking my brain and can't think of it in detail. Wish I could be more specific.

Bit of a pointless post really, sorry...

[KingEli]

Dr. Cain: Wow Dr. Light was a genius! Now I will copy Mega Man X's design sans all testing and prep Light to make sure X wasn't a killing machine. There will be no Consequences whatsoever, I'm sure of it.

[The Drunkard Kid]

I'm sure Homer Simpson has done something where he moves something tiny that he shouldn't touch, then loads of massive things collapse. But I've been racking my brain and can't think of it in detail. Wish I could be more specific.

Bit of a pointless post really, sorry...

Off the top of my head, there was the Tree House of Horror where he kept screwing up the timeline with the time travel toaster.

Also, The Phantom Menace. The galaxy would be a different place if they didn't choose to disobey Yoda by training Annie, had dropped off Amidala with Jedi Master Chris Hansen, or ate Jar Jar.