Spidey villain with the most potential to be the most dangerous...

[BrotherUnitNo_4]

Even when they all team-up with each other, they can't really accomplish much for whatever reason. Another problem is, at this point, they all just feel too friendly with each other. It never feels like a serious team-up anymore so much as a few guys getting together for a week of fun, merriment, and a few weeks in a hospital/prison room.

I'd actually read that issue.

[DV1Band]

Yea, and Green Goblin would get them to team up again, use them all to make Spidey's life hell, then destroy them all when he was done. Doesn't matter if it's the Sinister Six, or Vulture, or Tombstone. Goblin will just get to all of them. The only exception would have been Roderick Kingsley, were he still a good character...