ASM 200 ends with Peter having saved Aunt May's life and confronted the burglar who killed his uncle, as well as embracing his powers.
Kraven's Last Hunt would function as a nice bookend, as Peter rises from the grave just as he begins his new life with Mary Jane.
The Clone Saga could have ended with Peter walking off into the sunset with Mary Jane to raise their child.
Spider-Girl has Peter happily married with children, living his life as a forensic scientist.
I imagine Peter's story having a happy ending along those lines.