Maybe not, but I can see them taking the relatively small risk of launching an alternate-universe mini with a Lesbian or bisexual Wonder Woman. If it goes badly, they can wipe it out wth a highly publicized Wonder Woman/Batman relationship (assuming the Superman relationship is done by then.) If it is well-received--well, then...but would the WB gamble the world's most recognizable superhero on it? I don't think so.
And I think the risk will get smaller and smaller in the near future, as same-sex marriage and LGTQ characters in other media become more visible and accepted.