Before someone says this has been done. This has only been done with a mainstream or movie blade. This is a composite blade. In other words this blade is all the versions of blade wrapped up into one.
The most specific differences is his equipment. The his normal swords may not work on Eddy. This...I don't know what it is..a lightsaber? This sword featured in the cartoon here:http://www.youtube.com/watch?v=oECTYzFwPj8#t=02m16s might be a threat to Ed. This blade has all the weapons and gear, etc that all the versions of Blade has ever used. And the physical capabilities too, this is including the physical feats he has shown in the anime. Especially the damage soaking abilities(where he is punched through multiple stone pillars, walls, and falls from an incredibly high castle and then said castle crumbles on top of him to which he casually walks away from. And he seems to be capable of being strong enough to send some sort of odd shockwave at enemies just by swinging his blade forwards as shown here: http://www.animeshippuuden.com/dubbe...nglish-dubbed/ (@17:00).
So who would win? I mean I have heard and seen that the vamps of twilight are incredibly durable. But then I see this: https://www.youtube.com/watch?v=KXg6dMJGL5k#t=02m31s and wonder otherwise..