Harry's presence always tended to piss me off in that show...
The reason why Spec was so good is because it have great depths to the characters. The overall theme of the show was the education and growth of Peter Parker. You watch people like Mary Jane, Flash, Gwen, Liz, etc. develop.
The villains being around for so long before they actually become supervillains builds some sort of starting point to things happening in New York.There were so many villains in the first episode that you were going crazy to witness how they were going to decend into supervillainy.
Eddie Brock had a story that rivals a villain from BTAS. While he's generally a good guy, who does have morals, he does have some mental issues that started to slip out as the first season went on. We know his parents died when he was young, and we could guess he was bounced around from foster home to foster home as a child. Not being "wanted" obviously has affected him to the point where he's become very petty and relies on a parasite to "love" him. So much to the point that he forces himself to hate Peter/Spider-Man just to keep the symbiote which is just using him to feed off of his negative emotions. From his last appearance, it seems that he doesn't even know why he hates Peter anymore...he forces himself to. I remember wondering why he didn't just put two and two together of Peter's little mishaps when the symbiote first showed him the truth behind Spider-Man. However by Identity Crisis, I'm sure he understood why Peter seemed to be screwing people over...he just doesn't care anymore. He truly is a broken man...although he's only 19, you can't help but feel sorry for him.