Oh, Otto, what have you done?
This is it, this is really it. The proverbial s_ has hit the ceiling and it's reached a point of no return.
Ok, that's one of my initial reactions. The second is, I wish Dan had thrown me, pedroparkero, Dagman, and others a bone.
end of spoilers
With S.H.I.E.L.D. bearing down on the three they are placed under arrest and Rhino freed but they make good on their escape.
Sable pushes Sandman to confess (for you Horizon Labs wannabees, the acid she used is most likely hydrogen fluoride based that affects silica but leaves plastic, like her bottle, unaffected) as Spidey inches ever so closer to crossing his "no one dies" line. (Foreshadowing?)
People on the street worldwide voice their support for Otto (none from the Philippines?) as Chameleon and Mysterio debate continuing the plan with the cash already in. Otto extends offer to more supervillains to help him (I recognize Crossbones), but Titanium Man rats on him to Widow. Tipped, Spidey calls in help from superheroes worldwide (again, none from the Philippines?) and they do their part. Spidey thanks Sable for the words of support, as MJ goes into an interior monologue about her own confidence in Peter (with Jonah unwittingly contributing). (Again, another foreshadowing about the Peter/MJ relationship?)
The three track Otto's largest facility in Romania right next to Symkaria, only to have Otto tell them it's deserted, everything's in place, and with the flick of a switch, starts to burn up half of Earth, including Symkaria. And why the hell? Coz he can't bear inferior folks outliving him, to oversimplify it.
Dan, oh Dan, where are you taking this next? You've raised the stakes so high, it's scary.