All the things that would make me buy a Punisher comic are all the things that would violate just who the character really is. I like my comics less realistic, more crazy and colorful. To me, the existence of the Punisher in the Marvel U. is like a damper on the fun, nutty things I like to read. Whenever Punisher crosses over with those parts of the Marvel U, inevitably those parts of Marvel U suffer. Because the Punisher usually kills them.
Long story short - What would make me read the Punisher? Probably nothing. I like that he is around for those who enjoy those kinds of comics, but they're just not up my alley. I don't think he should have to change, either.