The title "Civil War: House of M" isn't just a clever combination of the titles of two of Marvel's biggest event comics, it's a literal description of what happens in the story. "It's a civil war in the sense that humanity and mutankind are at war," explained Gage.
As for the plot, it's the story of Magneto's rise to power. You'll see him meet and ally with Charles Xavier. You'll see Quicksilver and Polaris fight at his side (with Wanda in a non-combat role), initially not knowing they're his children. And you'll see what sacrifices have to be made for the dream to become reality."
For Magneto's dream to become reality, he'll also have to overcome a multitude of adversaries. "Well, needless to say, there are Sentinels galore," Gage confirmed. "In the first issue, Magneto finds himself battling Apocalypse for the right to chart the direction of the mutant resistance movement. And as he consolidates his power, the U.S. will send some of their top agents after him--including a former young ally of Captain America."
Given its sprawling scope, "Civil War: House of M" will feature large supporting cast. "The major supporting characters are Charles Xavier and the rest of the House of M-Quicksilver, Wanda, and Polaris," Gage revealed.