I tend to agree with Mr. Grant in that many of the comics that deal with religion (or at least their respective authors' take on the subject) tend to come off as slightly overwrought, teetering on melodrama at times. Granted (no pun intended), straight-up good vs. evil iconography is pretty much a given in the medium, when one considers Vertigo Comics' (the particular example SG brings up in this week's column) historical and genealogical ties to the superhero genre.
Still, even with that knowledge coming in, I find little to interest me in, say, Mike Carey's Lucifer or even the much-vaunted Sandman outside of the excellent level of craft that goes/went into them (I haven't read a single Neil Gaiman interview in my life but I'd always thought that there were some parallels being drawn between Morpheus and the semi-historical Jesus Christ... so if this was the author's intention or not, or if it was something I was just reading into the material, I'm not sure).
Even Garth Ennis' Preacher, possibly the pinnacle of "pissing on religious convention" comics during Vertigo's, for lack of a better term, "industry media renaissance", held my attention only insofar as the character interactions were of (possibly prurient and morbid) interest to me (Tulip cheating on Custer and sleeping with Cassidy, Odin Quincannon's love affair with meat-products, Arsefaces' uh, arse-face, etc.). The over-arching theme that was supposed to tie the whole series together, of some cosmic über-Judeo-Christian God-power being let loose in the world in the body of a conflicted man-of-the-cloth, sort of lost steam towards the end of the series, and to be honest, I found the ending sorely disappointing and anti-climactic. Part of the reason is that I could smell the ending from a good telegraphing-distance away... not the particulars, mind you, but the general idea, at the very least.
Despite my qualms, though, I don't find myself as critical of these comics as SG does. It maybe a function of age... I discovered these books when I was a disillusioned Catholic teen, caught between atheism and Buddhism (I'll let you guess where I eventually settled on... here's a clue, I work in a lab... although I should probably have been looking to critical/reviewed texts instead of North American comics for direction... The Waiting Place is not The Theological Review). I mean, they got me thinking about religion, at least, which is more than you can say about a lot of the stuff out there. And to that extent, I think they have some value outside of the authors soapboxing and such.