This interview and this thread will contain SPOILERS
An interview with Mike Carey at: marvel.com, link: http://184.108.40.206/blogs/Agent_M/entry/557
We will have Exodus in the Annual X-Men, he has a re-incarnation of a former villain team alongside (could be either the Brotherhood or the Acolytes if you ask me)
Mr. Sinister will make a small appearance in January and he has major plans for his 20th anniversary later that year, something huge!!
Also seems to me a new villain is shown, called Cadena, I think she's also one of 'the Children'.